InT@Columbia Journal Club—Summer 2023
By Elisa Huang
This summer, InT@Columbia organized a series of journal club presentations, which created a platform for those who are interested in biology and biomedical science to share the latest discoveries/research articles in different sub-fields.
Check out the list of the presenters and the topics covered in the past presentations.
07/15/23
Coco: Békés, M., Langley, D.R. & Crews, C.M. PROTAC targeted protein degraders: the past is prologue. Nat Rev Drug Discov 21, 181–200 (2022). https://doi.org/10.1038/s41573-021-00371-6
Sophia:
Mahapatra MK, Karuppasamy M, Sahoo BM. Semaglutide, a glucagon like peptide-1 receptor agonist with cardiovascular benefits for management of type 2 diabetes. Rev Endocr Metab Disord. 2022 Jun;23(3):521-539. doi: 10.1007/s11154-021-09699-1.
James:
Yang, J. H., Hayano, M., Griffin, P. T., Amorim, J. A., Bonkowski, M. S., Apostolides, J. K., ... & Sinclair, D. A. (2023). Loss of epigenetic information as a cause of mammalian aging. Cell, 186(2), 305-326. https://doi.org/10.1016/j.cell.2022.12.027
Aletta:
Hong Gao, Zhongmou Jin, Gautam Bandyopadhyay, Karina Cunha e Rocha, Xiao Liu, Huayi Zhao, Dinghong Zhang, Hani Jouihan, Soheil Pourshahian, Tatiana Kisseleva, David A. Brenner, Wei Ying, Jerrold M. Olefsky, MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH, Cell Metabolism, Volume 34, Issue 7, 2022, Pages 978-990.e4, ISSN 1550-4131, https://doi.org/10.1016/j.cmet.2022.05.008.
Claire:
Doke, T., Abedini, A., Aldridge, D.L. et al. Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis. Nat Immunol 23, 947–959 (2022). https://doi.org/10.1038/s41590-022-01200-7
07/29/23
Sophia: Liput KP, Lepczyński A, Ogłuszka M, Nawrocka A, Poławska E, Grzesiak A, Ślaska B, Pareek CS, Czarnik U, Pierzchała M. Effects of Dietary n-3 and n-6 Polyunsaturated Fatty Acids in Inflammation and Cancerogenesis. Int J Mol Sci. 2021 Jun 28;22(13):6965. doi: 10.3390/ijms22136965.
Elisa: Hu, Y., Yang, Y., Tan, P. et al. Induction of mouse totipotent stem cells by a defined chemical cocktail. Nature 617, 792–797 (2023). https://doi.org/10.1038/s41586-022-04967-9
James: Burdziak, C., Alonso-Curbelo, D., Walle, T., Reyes, J., Barriga, F. M., Haviv, D., ... & Pe’er, D. (2023). Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis. Science, 380(6645), eadd5327. doi: 10.1126/science.add5327
Cindy: Lashgari, Naser-Aldin et al. “The involvement of JAK/STAT signaling pathway in the treatment of Parkinson's disease.” Journal of neuroimmunology vol. 361 (2021): 577758. doi:10.1016/j.jneuroim.2021.577758
8/20/23
Emma: A high throughput bispecific antibody discovery pipeline https://doi.org/10.1038/s42003-023-04746-w
Coco: CAR T therapy beyond cancer: the evolution of a living drug https://www.nature.com/articles/s41586-023-06243-w
Claire: Exposure to lung-migrating helminth protects against murine SARS-CoV-2 infection through macrophage-dependent T cell activation https://www.science.org/doi/10.1126/sciimmunol.adf8161
Shawn: Characterizing the tumor microenvironment at the single-cell level reveals a novel immune evasion mechanism in osteosarcoma https://www.nature.com/articles/s41413-022-00237-6
Here are the Zoom recordings of the presentations:
07/15/23
https://drive.google.com/file/d/1IrLXdnGAOhmwjNt-UX4tytwIQWpGhlUO/view?usp=sharing
07/29/23
https://drive.google.com/file/d/1BT7VYu9Z6GA68CZa_rx109PVzYBnVffc/view?usp=sharing
08/20/23
https://drive.google.com/file/d/18bvadXytzbu2FSG1EyWfKhl2DPkYXWzM/view?usp=sharing
We are planning more in-person and online events to spread the scientific knowledge. Follow us on Linkedin, and Wechat (In Transcription生科平台) to stay updated on our latest news!
